The most frequently reported side effects of Nolvadex are excessive facial blushing and vaginal dryness. However, this is certainly not a indication of a more serious issue. The second most frequent side effect is female vaginal discharge. If the vaginal discharge is blood stained, it may be a sign of an underlying problem Nolvadex.
It is believed that women experiencing severe premenstrual syndrome may be prone to experiencing hot flashes as well. In such a case, using a placebo containing thensabp b-14 could possibly help relieve the premenstrual syndrome. One limitation of this study is that the administration of placebo can alter hormone levels, so the correlation between placebo and adverse effects cannot be established. Another limitation is that the use of thensabp b-14 was one-time and there was no comparison with placebo arm use in the two studies.
Nolvadex can potentially reduce the risk of developing male breast cancer. There is some evidence that it can decrease the risk of both men and women with breast cancer who have had radiation therapy. In addition, a number of preliminary investigations suggest that nolvadex may help to prevent prostate cancer and lessen the symptoms of both prostate cancer and prostatitis. Nolvadex has also been shown to help alleviate the symptoms of migraine and nausea in individuals that are undergoing chemotherapy.
Some patients taking tamoxifen citrate or other hormonal therapies (like nolvadex) have experienced urinary tract infections. Since these drugs are known to have a cystic form of hormone imbalance, patients can also experience infections if they are administered at the recommended dosage levels. It is important that these patients notify their doctors if they notice an infection. Cysts can sometimes be difficult to treat and might even require surgery. However, many doctors prefer to prescribe tamoxifen for patients that have moderate or mild bladder problems.
Patients who begin treatment with nolvadex two weeks or less before the start of any hormonal therapy should carefully monitor their blood levels and any changes in symptom. Nolvadex may cause a patient to have a change in mood or feel anxious or sleepy. There have been reports of nausea and vomiting in some patients using tamoxifen citrate or nolvadex. Patients should contact their doctor immediately if they experience any unusual side effects.
The safety of this medication was established by the Center for Drug Evaluation, which has evaluated this therapy for more than ten years. In patients with chronic prostatitis, irritable bowel syndrome or ulcerative colitis, the drug was well tolerated and showed no evidence of harm. Nolvadex was not tested against breast cancer or prostate cancer but it did not show evidence of altering the levels of testosterone in men or breast cancer in women. On the other hand, there were several case reports of increased risk of bleeding, vision problems and sexual dysfunction in men and women. The possibility of an Nolvadex-related event was considered very low but patients should contact their physician if they experience any unusual symptoms.